Skip to main content
v2026.11,772 entries · CC-BY 4.0
Dictionary termTrack BProposedv2026.2

Biorepository

A facility or organisation that collects, processes, stores, and distributes biological materials and their associated data for research, encompassing both human and non-human samples, distinguished from a 'biobank' by usage in some communities to denote broader scope or specific research projects.

ByCASRAI Editorial Board
· Last updated 23 Aug 2026
Share this

Ask CASRAI · included with Regulatory Radar

Ask about Biorepository

Ask CASRAI answers research-administration questions and cites the passages behind every claim — and says so when the corpus does not cover something, instead of guessing. It comes with a Regulatory Radar subscription at $29 a month, alongside the daily digest of regulatory changes and the dashboard of what changed.

150 questions a day, on this site, over the API, or inside your own tools through the CASRAI MCP server.

Everything CASRAI publishes — this page, the dictionary, the guides and the news — stays free to read, with no account and no card.

Examples

Worked examples

  • Is an instance

    A university's biorepository holding patient-derived xenograft mouse models and matched tumour specimens.

  • Is an instance

    An agricultural biorepository holding seed lines from crop-genetics research programmes.

Counter-examples

Looks similar, but isn't

  • Not an instance

    A clinical-care pathology lab is not a research biorepository.

  • Not an instance

    An archive of published research papers is not a biorepository.

Editorial commentary

The terms biobank, biorepository, and sample repository are used interchangeably in many communities; in others, ‘biorepository’ carries a broader connotation including animal models, plant material, microbial cultures, and environmental samples, while ‘biobank’ is reserved for human-focused collections. ISBER (International Society for Biological and Environmental Repositories) maintains the most widely used best-practice document. Biorepositories typically issue accession numbers and, increasingly, IGSN-style PIDs for samples.

References

  • ISBER, 'Best Practices for Repositories' (current edition).

ISBER Best Practices

ISBER (the International Society for Biological and Environmental Repositories) publishes the field’s most widely used best-practice document, covering specimen collection, processing, long-term storage and quality management, chain of custody, and cold-chain handling for both human and non-human biological material. Its recommendations are treated as the de facto operating standard by many institutional and commercial repositories, independent of ISBER accreditation itself.

Accessioning and persistent identifiers

Biorepositories typically assign an internal accession number to each specimen at intake, and an increasing number also mint external, globally resolvable persistent identifiers — most notably the IGSN (International Generic Sample Number), which functions for a physical sample much as a DOI functions for a publication or dataset, allowing a specimen to be cited and tracked independently of which repository or institution currently holds it.

References

  • ISBER, ‘Best Practices for Repositories’ (current edition).

Machine-readable encodings

Use in your systems

JATS XML <role> element
xml
<role vocab="credit"
      vocab-identifier="https://casrai.org/dictionary/"
      vocab-term="Biorepository"
      vocab-term-identifier="https://casrai.org/dictionary/term/biorepository" />
Schema.org DefinedTerm (JSON-LD)
json
{
  "@context": "https://schema.org",
  "@type": "DefinedTerm",
  "@id": "https://casrai.org/dictionary/term/biorepository",
  "name": "Biorepository",
  "identifier": "https://casrai.org/dictionary/term/biorepository",
  "description": "A facility or organisation that collects, processes, stores, and distributes biological materials and their associated data for research, encompassing both human and non-human samples, distinguished from a 'biobank' by usage in some communities to denote broader scope or specific research projects.",
  "inDefinedTermSet": "https://casrai.org/dictionary/domain/data-infrastructure#set",
  "url": "https://casrai.org/dictionary/term/biorepository",
  "sameAs": [],
  "license": "https://creativecommons.org/licenses/by/4.0/",
  "publisher": {
    "@id": "https://casrai.org/#organization"
  },
  "author": {
    "@id": "https://casrai.org/#editorial-team"
  },
  "datePublished": "2026-05-21T02:18:31",
  "dateModified": "2026-08-23T06:25:17",
  "inLanguage": "en-GB",
  "isAccessibleForFree": true
}

Referenced across the research world

University of Cambridge logoColumbia University logoCrossref logoUniversity of Edinburgh logoHarvard University logoUniversity of Oxford logoPrinceton University logoStanford School of Medicine logoUniversity College London logoORCID logoUniversity of Cambridge logoColumbia University logoCrossref logoUniversity of Edinburgh logoHarvard University logoUniversity of Oxford logoPrinceton University logoStanford School of Medicine logoUniversity College London logoORCID logo
  • University of Cambridge logo
  • Columbia University logo
  • Crossref logo
  • University of Edinburgh logo
  • Harvard University logo
  • University of Oxford logo
  • Princeton University logo
  • Stanford School of Medicine logo
  • University College London logo
  • ORCID logo

View CASRAI adoption →

Regulatory Radar

Stop finding out after the fact

$29/month, cancel anytime. Daily digest updates from our analysis, a dashboard holding the same items, and a cited assistant for everything they raise.

  • Federal Register, Federal Register+, Grants.gov, Regulations.gov, NSF News, UKRI, plus CASRAI’s own published content.
  • 72,264 indexed passages, and every answer cites the ones it drew on.