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v2026.11,772 entries · CC-BY 4.0
Dictionary termTrack EProposedv2026.2

Orphan (unclaimed) freezer sample

A sample held in ultra-low-temperature (ULT, -80 degC) or -20 degC cold storage with no identifiable current owner, provenance record, or active research use -- commonly called an orphan or unclaimed sample -- and a standard target for freezer clean-out and sustainability audits.

ByCASRAI Editorial Board
· Last updated 22 Aug 2026
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Examples

Worked examples

  • Is an instance

    A 2024 audit of a 600-litre -80 degC freezer found over a third of boxes had no identifiable owner and were dispositioned with PI sign-off.

  • Is an instance

    An institution mandates that any sample untouched for seven years is flagged as unclaimed and scheduled for destruction unless the owning lab claims it.

Counter-examples

Looks similar, but isn't

  • Not an instance

    A clearly labelled, actively used cell line in continuous publication output is not an orphan sample.

  • Not an instance

    A regulatory biobank sample subject to a statutory retention period is not orphaned even if dormant.

Editorial commentary

An orphan or unclaimed freezer sample is a sample held in ultra-low-temperature (ULT, -80°C) or -20°C cold storage with no identifiable current owner, provenance record, or active research use — typically because the original researcher has left the institution, a project ended without a retention decision, or lab turnover broke the chain of custody. “Orphan” and “unclaimed” are the terms actually used in the sustainability-in-laboratory and cold-storage-management literature.

Why it matters

An orphan sample consumes freezer energy indefinitely while delivering zero research value: the freezer runs the same compressor cycle whether the box inside it is needed tomorrow or has sat untouched for a decade. Because ULT freezers are among a lab building’s larger single energy draws, a freezer full of unclaimed material is a direct, avoidable operating cost, not just a housekeeping problem.

How institutions find and resolve them

Periodic freezer audits — reviewing rack contents against a current sample-ownership database — are the standard detection method, often run alongside a broader lab waste audit. A written retention policy sets a default disposition: samples untouched for a defined period, commonly cited in the roughly 5-10 year range across institutional policies though this varies by sample type and any applicable regulatory retention requirement, are flagged for owner confirmation and, absent a claim, scheduled for consolidation or disposal. Getting this right requires PI sign-off and a documented decision trail, since destroying a sample that turns out to still matter is a research-integrity risk, not merely an efficiency one.

Where this sits in cold-storage practice

Identifying and clearing orphan samples is a recurring theme in the annual International Freezer Challenge, run jointly by My Green Lab and the International Institute for Sustainable Laboratories (I2SL), and in institutional cold-storage best-practice guidance generally — alongside setpoint review and preventive maintenance, covered under -80 freezer management.

References

  • My Green Lab / I2SL International Freezer Challenge programme materials.

Also known as

Unknown Long-Abandoned Biological sample · Orphan sample · Unowned sample

Machine-readable encodings

Use in your systems

JATS XML <role> element
xml
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      vocab-term="Orphan (unclaimed) freezer sample"
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Schema.org DefinedTerm (JSON-LD)
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